Ovarian dysfunction (inability to ovulate normally on your own)
Infertility associated with endometriosis (a painful inflammatory condition of the female pelvis)
Cervical factor infertility (related to prior surgery)
Unexplained infertility (infertility in which the exact cause cannot be identified).
POLYCYSTIC OVARIAN SYNDROME (A COMMON FEMALE ENDOCRINE DISORDER)
Intrauterine insemination offers a multi-faceted approach to augmenting a couple’s fertility. For example, male infertility is a factor in about a third of all infertile couples, usually attributable to low sperm count, abnormal sperm or motility problems. By concentrating more sperm in the female reproductive tract, the odds of achieving a pregnancy increase.
The sperm are concentrated using a multi-step process called sperm washing. The technique removes excess seminal fluid that can cause cramping or pain if it is not washed away at the time of intrauterine insemination.
In other cases, inadequate cervical secretions and antibodies may act as barriers to sperm entering the female reproductive tract and penetrating the egg. IUI places the sperm beyond those barriers, again increasing the chances of fertilization and pregnancy.
IUI is an effective treatment for both male fertility problems and couples with unexplained infertility. In couples with unexplained infertility where all other testing is normal, intrauterine insemination (IUI) combined with ovulation induction/superovulation can double a couple’s chance for pregnancy.
Most physicians recommend three to six IUI attempts before moving on to more aggressive treatment.